Sherlock Holmes in the 22nd Century - Season 1 - Eps 10: The Sign of Four
Mary Morstan comes to Holmes with a problem. The solution of that problem, however, will lead them clear to the moon! Mary's father had been killed in a mine accident on the moon years ago. Now Mary is finding out that the circumstances were strange then, and the sequel is even stranger now.
About Sherlock Holmes in the 22nd Century

Title: Sherlock Holmes in the 22nd Century
First Air Date: 1999-09-18
Last Air Date: 2001-07-21
Status: Ended
Rating: 7.8/10 (from 13 votes)
Language: EN
Seasons: 2
Total Episodes: 26
Network: FOX Syndication Fox Kids
Genres: Animation, Mystery, Crime, Sci-Fi & Fantasy
Production Companies: DiC Entertainment, Scottish Television Enterprises
Synopsis
Sherlock Holmes in the 22nd Century is an animated television series, in which Sherlock Holmes is brought back to life in the 22nd century. The series is a co–production by DiC and Scottish Television and was nominated for a Daytime Emmy for Special Class Animated Program.
Cast

Jason Gray-Stanford
Sherlock Holmes (voice)

Akiko Morison
Inspector Beth Lestrade (voice)

John Payne
Dr. John Watson (voice)

Richard Newman
Professor James Moriarty (voice)

William Samples
Chief Inspector Greyson (voice)

Ian James Corlett
Martin Fenwick (voice)

Viv Leacock
Wiggins (voice)

Jennifer Copping
Deidre (voice)

Gillian Barber
(voice)

Kathleen Barr
(voice)